ISSN 2415-3060 (print), ISSN 2522-4972 (online)
  • 24 of 49
JMBS 2019, 4(4): 152–157
Clinical Medicine

Distinctive Parameters of Left Ventricle Remodeling among Hypertensive Patients

Fushtei І. М., Bayduzha O. M., Sid’ E.V., Soloviov O. V.

Hypertension currently occupies the leading position in morbidity and prevalence among all the cardiovascular diseases. The incidence of hypertension worldwide is a pandemic. The purpose of the study was to determine the characteristics of left ventricular remodeling in patients with hypertension of the second stage. Material and methods. In order to carry out the study, we carried out a comprehensive examination of 224 patients with hypertension, 126 of them had the second stage and 98 of them had the first stage of the disease. Verification of hypertension was carried out according to the order of the Ministry of Health of Ukraine. 35 almost healthy individuals were also examined. All the patients were comparable in age and social status. Echocardiography was performed in all the patients on the device "My Lab Seven" (Esaote, Italy) in m and b-modes according to the standard technique with the frequency of location equas to 1-5 MHz according to the generally accepted methods of the European Association of Cardiovascular Imaging, the American Society of Echocardiography. Results and discussion. The indicator of myocardial mass index between groups of patients with hypertension and stage and apparently healthy individuals had no significant difference (p > 0.05). While comparing the median with the value of this indicator in the group of healthy individuals equaled to 93.36 [88.43-105.44] g/m2 was highly significantly higher by 27.3 % in the group of patients with hypertension of the second stage (p < 0.05). The change in the relative wall thickness of the left ventricle was similar. Determination of myocardial mass index and relative wall thickness of the left ventricle made it possible to distinguish the types of left ventricular geometry in patients with hypertension of the second stage. It was determined that in the group of patients with hypertension of the second stage, eccentric and concentric left ventricular hypertrophy prevailed 49.2 % and 25.4 %, respectively. Conclusions. While studying the left ventricular remodeling parameters, certain changes were revealed between the groups of patients, which relate to the myocardial mass index, and were manifested by its significant increase in hypertensive disease of the second stage. Left ventricular remodeling in patients with the second stage of hypertension was observed in a larger proportion of patients with eccentric left ventricular hypertrophy.

Keywords: hypertension, myocardial mass index, echocardiography, types of left ventricular remodeling

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  1. Lashkul ZV. Osoblyvosti epidemiolohiyi arterialnoi hipertenziyi ta yiyi uskladnen na rehionalnomu rivni z 1999 po 2013 roky [Features of epidemiology of hyperpiesis and their complications at regional level from 1999 to 2013]. Suchasni medychni tekhnolohiyi. 2014; 2: 134-41. [Ukrainian]
  2. Yoon SS, Gu Q, Nwankwo T, Wright JD, Hong Y, Burt V. Trends in blood pressure among adults with hypertension: United States, 2003 to 2012. Hypertension. 2015; 65(1): 54-61.
  3. Gorshunova NK, Medvedev NV. Organy-mysheny y assotsyyrovannye klynycheskye sostoyanyya pry arteryalnoy gypertonyy [Organs-targets and associated clinical states at arterial high blood pressure]. Spravochnyk feldshera y akusherky. 2016; 7: 37-44. [Russian]
  4. González A, Ravassa S, López B, Moreno MU, Beaumont J, San José G, et al. Myocardial Remodeling in Hypertension: Toward a New View of Hypertensive Heart Disease. Hypertension. 2018; 72(3): 549-58.
  5. Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J. 2006; 27(21): 2588-605.
  6. Papaioannou TG, Protogerou A, Papamichael C, Mathioulakis D, Tsangaris S, Karatzis E, et al. Experimental and clinical study of the combined effect of arterial stiffness and heart rate on pulse pressure; differences between central and peripheral arteries. Exp Pharmacol Physiol. 2005; 32(3): 210-7.
  7. Golemati S, Stoitsis JS, Gastounioti A, Dimopoulos AC, Koropouli V, Nikita KS. Comparison of block matching and differential methods for motion analysis of the carotid artery wall from ultrasound images. Transactions on Information Technology in Biomedicine. 2012; 16(5): 852-8.
  8. Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Cheng S, et al. Relations of central hemodynamics and aortic stiffness with left ventricular structure and function: the Framingham Heart Study. Journal of the American Heart Association. 2016; 5(3): e002693.
  9. Arterialna hipertenziya. Onovlena ta adaptovana klinichna nastanova, zasnovana na dokazakh [Hyperpiesis. Renewed and the adapted clinical discipling based on proofs]. Asotsiatsiya kardiolohiv Ukrainy. K; 2012. 139 p. [Ukrainian]
  10. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Journal of the American Society of Echocardiography. 2015; 28(1): 1-39.
  11. Konrady AO, Rudomanov OG, Zakharov DV. Varyanty remodelyrovanyya serdtsa pry gypertonycheskoy bolezny-rasprostranennost y determynanty [Hypertensive heart remodeling options - prevalence and determinants]. Terapevtycheskyy arkhyv. 2005; 9(77): 8-16. [Russian]
  12. Bartnik M, Rydén L, Ferrari R, Malmberg K, Pyörälä K, Simoons M, et al. The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe: The Euro Heart Survey on diabetes and the heart. European heart journal. 2004; 25(21): 1880-90.